Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 6V1E
TargetBromodomain-containing protein 7(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  121nMAssay Description:Binding affinity to recombinant human His-tagged BRD7 (129 to 250 residues) expressed in Escherichia coli BL21 DE3 assessed as dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 7(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  0.316nMAssay Description:Binding affinity to BRD7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 7(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to human BRD7 by BROMOScan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 7(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 117nMAssay Description:Inhibition of human N-terminal GST-tagged BRD7 expressed in Escherichia coli using tetra-acetylated histone H4 measured after 60 mins by AlphaScreen ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 7(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 117nMAssay Description:Inhibition of human BRD7 measured after mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 7(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of NanoBRET BRD Tracer-02 from Nanoluc-fused BRD7 bromodomain (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 7(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of FAM-labeled BI-FAMb from N-terminal His TEV-tagged human recombinant BRD7 bromodomain expressed in Escherichia coli BL21(DE3) by comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 7(Human)
Moffitt Cancer Center

Curated by ChEMBL
LigandPNGBDBM50183448(CHEMBL3823478 | US11773085, Compound B2)
Affinity DataKi:  300nMAssay Description:Displacement of FAM-labeled BI-FAMb from N-terminal His TEV-tagged human recombinant BRD7 bromodomain expressed in Escherichia coli BL21(DE3) by comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)