Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6XVP
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085452(Sampatrilat | (S)-2-[((S)-6-Amino-2-methanesulfony...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeprilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085452(Sampatrilat | (S)-2-[((S)-6-Amino-2-methanesulfony...)
Affinity DataIC50: 8nMAssay Description:Inhibition of NEP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeprilysin(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085452(Sampatrilat | (S)-2-[((S)-6-Amino-2-methanesulfony...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)