Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6YDX
TargetLeucyl-cystinyl aminopeptidase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeucyl-cystinyl aminopeptidase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLeucyl-cystinyl aminopeptidase(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331042(2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in absence of 30 mM EDTA/600 uM 1,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)