Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) for PDB: 6YOJ
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant FAK (410 to 689 residues) (unknown origin) using Poly (4:1 Glu, Tyr) peptide as substrate enzyme pretreated with substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 4nMAssay Description:Inhibition of GST-FAK domain (410-689) (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant FAK (410 to 689 residues) (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 4nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 4nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 11nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human A431 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 30nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human FG cells after 60 mins by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 50nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human SKOV3 cells after 60 mins by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 100nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human PC3 cells after 60 mins by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 300nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human L3.6pl cells after 60 mins by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)