Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 6Z0Z
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581792(CHEMBL5093813)
Affinity DataEC50:  20nMAssay Description:Activation of wild-type human STING expressed in digitonin treated HEK293T cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581792(CHEMBL5093813)
Affinity DataEC50:  1.03E+3nMAssay Description:Activation of wild-type human STING expressed in human THP1-Dual cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activation measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581792(CHEMBL5093813)
Affinity DataEC50:  7.99E+3nMAssay Description:Activation of wild-type human STING expressed in HEK293T cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activation measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581792(CHEMBL5093813)
Affinity DataEC50:  1.91E+4nMAssay Description:Activation of wild-type human STING expressed in digitonin treated human THP1-Dual cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581792(CHEMBL5093813)
Affinity DataEC50:  9.65E+4nMAssay Description:Activation of wild-type human STING expressed in HEK293T cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activation measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)