Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 7ACK
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute For Organic Syntheses (Vuos)

Curated by ChEMBL
LigandPNGBDBM50563675(CHEMBL4762791)
Affinity DataIC50: 660nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) using peptide substrate in presence of [gamma33P]ATP by image analyserMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Institute For Organic Syntheses (Vuos)

Curated by ChEMBL
LigandPNGBDBM50563675(CHEMBL4762791)
Affinity DataIC50: 680nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin) using peptide substrate in presence of [gamma33P]ATP by image analyserMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Institute For Organic Syntheses (Vuos)

Curated by ChEMBL
LigandPNGBDBM50563675(CHEMBL4762791)
Affinity DataKd:  4.10E+3nMAssay Description:Binding affinity to CDK2 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)