Report error Found 4 Enz. Inhib. hit(s) for PDB: 7ARG
Affinity DataIC50: 90nMAssay Description:Inhibition of human Notum (81 to 451 Cys330Ser) using OPTS as substrate incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 93nMAssay Description:Covalent inhibition of glycosylated Notum 1 (unknown origin) using OPTS as reporter substrate incubated for 40 mins by microplate reader based analys...More data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of human recombinant Notum (81 to T451 residues) expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by microplate re...More data for this Ligand-Target Pair
Affinity DataEC50: 530nMAssay Description:Inhibition of Notum 1 (unknown origin) expressed in HEK293 cells harbouring TCF/LEF luciferase reporter gene assessed as modulation of Wnt/beta-caten...More data for this Ligand-Target Pair