Report error Found 5 Enz. Inhib. hit(s) for PDB: 7C3N
TargetTyrosine-protein kinase JAK3(Human)
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of JAK 3 (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetTyrosine-protein kinase JAK3(Human)
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human JAK3 (781 to end residues) in the presence of [gamma p33]-ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Human)
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human JAK3 (780 to end residues) expressed in baculovirus infected Sf9 cells using TK-substrate-biotin as substrate incubated for 60 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of JAK1/JAK3 in human PBMC assessed as reduction in IL2-induced Stat5 phosphorylation in CD3+CD4+ cells preincubated for 30 mins followed ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Human)
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Csir-Indian Institute of Integrative Medicine
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Inhibition of JAK3 JH1 domain (unknown origin) using Carboxyfluorescein-Ahx-GGEEEEYFELVKKKK peptide as substrate incubated for 60 mins in the presenc...More data for this Ligand-Target Pair