Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 7CKX
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116(CHEMBL291143 | cid_6603703 | (1R,3S)-3-Adamantan-1...)
Affinity DataEC50:  3nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Pig)
Shaanxi University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50033116(CHEMBL291143 | cid_6603703 | (1R,3S)-3-Adamantan-1...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]SCH-23390 from porcine striatum dopamine D1 receptor incubated for 30 mins by radioligand competition binding assay based scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Rat)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50033116(CHEMBL291143 | cid_6603703 | (1R,3S)-3-Adamantan-1...)
Affinity DataEC50:  5.10nMAssay Description:Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116(CHEMBL291143 | cid_6603703 | (1R,3S)-3-Adamantan-1...)
Affinity DataKi:  21nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Rat)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50033116(CHEMBL291143 | cid_6603703 | (1R,3S)-3-Adamantan-1...)
Affinity DataKi:  30nMAssay Description:In vitro binding affinity against Dopamine receptor D1 like from rat caudate membrane using [125I]-SCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)