Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7CR4
LigandPNGBDBM64871(N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...)
Affinity DataEC50:  980nMAssay Description:Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM64871(N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...)
Affinity DataEC50:  5.80E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Mode of Action, Electrophysiology Source (MLPCN Center Name): Johns Hopkins Ion Channel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssayPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM64871(N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...)
Affinity DataEC50:  5.90E+3nMAssay Description:Data Source: Johns Hopkins Ion Channel Center BioAssay Type: Mode of Action, Electrophysiology Source (MLPCN Center Name): Johns Hopkins Ion Channel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssayPDB3D3D Structure (crystal)
TargetPotassium voltage-gated channel subfamily KQT member 2(Human)
Shanghai Zhimeng Biopharma

US Patent
LigandPNGBDBM64871(N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...)
Affinity DataEC50:  8.23E+3nMAssay Description:Cell preparation: CHO-KCNQ2 cells were cultured in a 175 cm2 culture flask, and when the cells was grown to a density of 60-80%, the culture medium w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)