Affinity DataEC50: 390nMAssay Description:Partial agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes by voltage clamp electrophysiological methodMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 250nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in Ach-induced current at -90 mV membra...More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Activity at human alpha-7 nACh receptor expressed in Xenopus laevis oocyte assessed as increase in acetylcholine-induced currentMore data for this Ligand-Target Pair
Affinity DataEC50: 158nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in rat GH4C1 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.80E+3nMAssay Description:Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...More data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Binding affinity to human alpha7 nAchRMore data for this Ligand-Target Pair
Affinity DataKi: 9.98nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
