Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 7JNX
TargetCarbonic anhydrase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM16668(CHEMBL23579 | 2,2-dimethyl-N-(5-sulfamoyl-1,3,4-th...)
Affinity DataKi:  0.660nMAssay Description:Inhibition of recombinant human CA2 expressed in Escherichia coli BL21 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM16668(CHEMBL23579 | 2,2-dimethyl-N-(5-sulfamoyl-1,3,4-th...)
Affinity DataKi:  9nMAssay Description:Inhibitory effect on human Carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM16668(CHEMBL23579 | 2,2-dimethyl-N-(5-sulfamoyl-1,3,4-th...)
Affinity DataKi:  10nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)