Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7JOZ
TargetD(1A) dopamine receptor(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50535447(CHEMBL4453318)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at wild type human D1R expressed in HEK293 cells assessed as effect on cAMP accumulation incubated for 10 mins by Gs-cAMP Glosensor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50535447(CHEMBL4453318)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human D1 receptor stably expressed in HEK293 cells assessed as induction of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50535447(CHEMBL4453318)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]-SCH23390 from wild type human D1R expressed in HEK293 cell membranes incubated for 90 mins by scintillation counting based compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50535447(CHEMBL4453318)
Affinity DataEC50:  35nMAssay Description:Agonist activity at wild type human D1R expressed in HEK293 cells assessed as effect on beta-arrestin2 recruitment by PRESTO-Tango beta-arrestin2 rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)