Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 7L50
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567001(CHEMBL4873898)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to human His-tagged MAGL assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567001(CHEMBL4873898)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)