Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7LD9
TargetGlutathione hydrolase 1 proenzyme(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50104413(Glutamyl-gamma-boronate analogue | CHEMBL87796)
Affinity DataKi:  5nMAssay Description:Inhibition of GGT1 (unknown origin) transpeptidation assessed as inhibition constant using L-GpNA as substrate in presence of Gly-GlyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutathione hydrolase 1 proenzyme(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50104413(Glutamyl-gamma-boronate analogue | CHEMBL87796)
Affinity DataKi:  5.40nMAssay Description:Inhibition of human GGT1 transpeptidation in Pichia pastoris using L-GpNA as substrate in presence of Gly-GlyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutathione hydrolase 1 proenzyme(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50104413(Glutamyl-gamma-boronate analogue | CHEMBL87796)
Affinity DataKi:  25nMAssay Description:Inhibition of human GGT1 expressed in Pichia pastoris assessed as inhibition of GSH hydrolysis measured by L-glutamate release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutathione hydrolase 1 proenzyme(Human)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50104413(Glutamyl-gamma-boronate analogue | CHEMBL87796)
Affinity DataKi:  25nMAssay Description:Inhibition of GGT1 (unknown origin) assessed as GSH hydrolysis by measuring inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)