Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7MFC
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM50589669(Dcc-3014 | Vimseltinib | DCC-3014 | DP-6865 | VIMS...)
Affinity DataIC50: 2.20nMAssay Description:The activity of CSF1R kinase (CSF1R, SEQ ID NO: 1) was determined spectroscopically using a coupled pyruvate kinase/lactate dehydrogenase assay that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM50589669(Dcc-3014 | Vimseltinib | DCC-3014 | DP-6865 | VIMS...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of 4 mM ATP measured by cell-based spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM50589669(Dcc-3014 | Vimseltinib | DCC-3014 | DP-6865 | VIMS...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Deciphera Pharmaceuticals

US Patent
LigandPNGBDBM50589669(Dcc-3014 | Vimseltinib | DCC-3014 | DP-6865 | VIMS...)
Affinity DataIC50: 27nMAssay Description:Inhibition of CSF1R in CSF1-stimulated human THP-1 cells assessed as inhibition of CSF1R phosphorylation measured by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)