Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7OAI
TargetPeripheral plasma membrane protein CASK(Human)
Goethe University Frankfurt Am Main

Curated by ChEMBL
LigandPNGBDBM50425829(CHEMBL2312304)
Affinity DataKd:  4.60nMAssay Description:Binding affinity to human CASK by KINOMEscan scanMAX assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeripheral plasma membrane protein CASK(Human)
Goethe University Frankfurt Am Main

Curated by ChEMBL
LigandPNGBDBM50425829(CHEMBL2312304)
Affinity DataKd:  87nMAssay Description:Binding affinity to recombinant N-terminal His-tagged CASK (1 to 337 residues) (unknown origin) expressed in Escherichia coli assessed as dissociatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeripheral plasma membrane protein CASK(Human)
Goethe University Frankfurt Am Main

Curated by ChEMBL
LigandPNGBDBM50425829(CHEMBL2312304)
Affinity DataIC50: 130nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused CASK (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeripheral plasma membrane protein CASK(Human)
Goethe University Frankfurt Am Main

Curated by ChEMBL
LigandPNGBDBM50425829(CHEMBL2312304)
Affinity DataKi:  15nMAssay Description:Inhibition of tracer K5 binding to NanoLuc-fused CASK (unknown origin) expressed in HEK293T cells measured after 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)