Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7OFK
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50575029(CHEMBL4864604)
Affinity DataIC50: 40nMAssay Description:Inhibition of human RORgamma by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50575029(CHEMBL4864604)
Affinity DataIC50: 41nMAssay Description:Inverse agonist activity at human RORC2 assessed as inhibition of SRC1-derived coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50575029(CHEMBL4864604)
Affinity DataIC50: 73nMAssay Description:Inverse agonist activity at human RORC ligand binding domain incubated for 30 mins by scintillation proximity binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575029(CHEMBL4864604)
Affinity DataIC50: 84nMAssay Description:Inverse agonist activity at mouse RORC ligand binding domain incubated for 30 mins by scintillation proximity binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)