Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 7P2M
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50568726(CHEMBL4854181 | US12258342, Example 9)
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit B(Escherichia coli)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50568726(CHEMBL4854181 | US12258342, Example 9)
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli full length wildtype GyrB24 (residue 1 to 220) supercoiling in presence of pNO1 plasmid incubated for 30 mins by micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit B(Escherichia coli)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50568726(CHEMBL4854181 | US12258342, Example 9)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Escherichia coli full length wildtype GyrB24 (residue 1 to 220) assessed as ATP-independent relaxation for 2 hrs in presence of pBR322 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)