Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 7P2N
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Univerza V Ljubljani

US Patent
LigandPNGBDBM50568720(CHEMBL4862321 | US12258342, Example 13)
Affinity DataIC50: 5nMAssay Description:First, the plates were rehydrated with buffer (20 mM Tris-HCl with pH 7.6, 0.01% w/v BSA, 0.05% v/v Tween 20, 137 mM NaCl) and the biotinylated oligo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Univerza V Ljubljani

US Patent
LigandPNGBDBM50568720(CHEMBL4862321 | US12258342, Example 13)
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)