Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7PWY
LigandPNGBDBM261607(US9708272, 18 | US10513499, Compound 18 | US112546...)
Affinity DataIC50: 10nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (3OH-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM261607(US9708272, 18 | US10513499, Compound 18 | US112546...)
Affinity DataIC50: 10nMAssay Description:The activity of compounds 1-19 and 21-23 as inhibitors of ACMSD1 was determined by measuring the conversion of 3OH-Anthranilic Acid into product (i.e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2022
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM261607(US9708272, 18 | US10513499, Compound 18 | US112546...)
Affinity DataIC50: 10nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (30H-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM261607(US9708272, 18 | US10513499, Compound 18 | US112546...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)