Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 7Q6T
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to ATAD2 bromodomain (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) by BROMOscan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 7nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 50nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 79nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 100nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 126nMAssay Description:Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2A BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)