TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard
Curated by ChEMBL
Institute of Mit and Harvard
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
3D Structure (crystal)TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard
Curated by ChEMBL
Institute of Mit and Harvard
Curated by ChEMBL
Affinity DataEC50: 3.80E+3nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1More data for this Ligand-Target Pair
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard
Curated by ChEMBL
Institute of Mit and Harvard
Curated by ChEMBL
Affinity DataIC50: 8.42E+3nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hrs in presence of glutathione and glutathione reductase by microplate reader analysisMore data for this Ligand-Target Pair
