Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7U9A
TargetEpidermal growth factor receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50602085(CHEMBL5206697)
Affinity DataIC50: 12nMAssay Description:Inhibition of EGFR (unknown origin) Del19 mutant preincubated with compound 30 mins followed ATP addition incubated for 30 mins by HTRF KinEASE TK as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50602085(CHEMBL5206697)
Affinity DataIC50: 19nMAssay Description:Inhibition of EGFR (unknown origin) L858R mutant preincubated with compound 30 mins followed ATP addition incubated for 30 mins by HTRF KinEASE TK as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50602085(CHEMBL5206697)
Affinity DataIC50: 609nMAssay Description:Inhibition of EGFR (unknown origin) L858R/T790M mutant preincubated with compound 30 mins followed ATP addition incubated for 30 mins by HTRF KinEASE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50602085(CHEMBL5206697)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) preincubated with compound 30 mins followed ATP addition incubated for 30 mins by HTRF KinEASE TK assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)