Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7UL2
TargetNeurotensin receptor type 1(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50248034(CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...)
Affinity DataIC50: 0.990nMAssay Description:Displacement of [125I]I-Tyr(3)NT from human NTR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeurotensin receptor type 1(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50248034(CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...)
Affinity DataKd:  8.90nMAssay Description:Displacement of [3H]SR48692 from wild type human NTR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeurotensin receptor type 1(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50248034(CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at NTSR1 (unknown origin) expressed in CHO cells assessed as inhibition of NT(8-13) peptide-induced change in intracellular Ca2+ ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeurotensin receptor type 1(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50248034(CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...)
Affinity DataEC50:  3.10E+4nMAssay Description:Agonist activity at NTR1 in human U2OS cells after 1 hr by beta-arrestin GFP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)