Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 7UOS
TargetSerine/threonine-protein kinase WNK1(Human)
The University of Texas Southwestern Medical Center At Dallas

Curated by ChEMBL
LigandPNGBDBM50595744(CHEMBL5178104)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of TEV cleavage site-fused His6-tagged WNK1 (194 to 483 residues) (unknown origin) expressed in Rosetta (DE3) cells using GST-OSR1(314 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase WNK1(Human)
The University of Texas Southwestern Medical Center At Dallas

Curated by ChEMBL
LigandPNGBDBM50595744(CHEMBL5178104)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of TEV cleavage site-fused His6-tagged WNK1 (194 to 483 residues) (unknown origin) expressed in Rosetta (DE3) cells using GST-OSR1(314 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase WNK1(Human)
The University of Texas Southwestern Medical Center At Dallas

Curated by ChEMBL
LigandPNGBDBM50595744(CHEMBL5178104)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of WNK1 in human MDA-MB-231 cells assessed as reduction in OSR1 phosphorylation measured after 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)