Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 7WYY
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
Windtree Therapeutics

US Patent
LigandPNGBDBM50605867(CHEMBL469045 | US12343350, Compound ISTAROXIME)
Affinity DataIC50: 140nMAssay Description:Na,K-ATPase activity was assayed in vitro by measuring the release of 32P-ATP, as described previously (see Ferrandi M. et al., Hypertension 1996; 28...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
Windtree Therapeutics

US Patent
LigandPNGBDBM50605867(CHEMBL469045 | US12343350, Compound ISTAROXIME)
Affinity DataIC50: 140nMAssay Description:Inhibition of Beagle dog kidney NA+/K+ ATPase alpha 1 by measuring 32P-ATP hydrolysis preincubated for 10 mins followed by addition of 32P-ATP measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)