Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 7X2D
TargetD(1A) dopamine receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM160918(US9107923, 7 | US9107923, 8 | US11014909, Example ...)
Affinity DataKi:  8.5nMAssay Description:Partial agonist activity at human D1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM289097(US10093655, Example 7 | (−)-1,5-Dimethyl-6-(...)
Affinity DataKi:  8.54nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM160918(US9107923, 7 | US9107923, 8 | US11014909, Example ...)
Affinity DataKi:  8.54nMAssay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM160918(US9107923, 7 | US9107923, 8 | US11014909, Example ...)
Affinity DataKi:  8.54nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM289098(US10093655, Example 8 | (+)-1,5-Dimethyl-6-(2-meth...)
Affinity DataKi:  21nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM160918(US9107923, 7 | US9107923, 8 | US11014909, Example ...)
Affinity DataKi:  21nMAssay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM160918(US9107923, 7 | US9107923, 8 | US11014909, Example ...)
Affinity DataKi:  21nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)