Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 7XM2
TargetKelch-like ECH-associated protein 1(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50571811(CHEMBL4856564)
Affinity DataKd:  230nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged human KEAP1 Kelch domain (322 to 609 residues) expressed in Escherichia coli BL21 (DE3) by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetKelch-like ECH-associated protein 1(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50571811(CHEMBL4856564)
Affinity DataKd:  230nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human Keap1-Nrf2 (322 to 609 residues) (unknown origin) protein-protein interaction expressed in Esc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetKelch-like ECH-associated protein 1(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50571811(CHEMBL4856564)
Affinity DataKi:  95nMAssay Description:Inhibition of Keap1 (unknown origin)/Nrf2 (unknown origin) protein-protein interaction assessed as inhibition constant by fluorescence anisotropy ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)