Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 7XR6
TargetExcitatory amino acid transporter 2(Human)
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARA...)
Affinity DataKi:  85nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetExcitatory amino acid transporter 2(Human)
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARA...)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against glutamate uptake in oocytes expressing in human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetExcitatory amino acid transporter 2(Human)
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARA...)
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetExcitatory amino acid transporter 2(Human)
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARA...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetExcitatory amino acid transporter 2(Human)
Wyeth Research

Curated by PDSP Ki Database
LigandPNGBDBM86712(N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARA...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)