Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7XTQ
TargetG-protein coupled bile acid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human TGR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled bile acid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  10nMAssay Description:Agonist activity at GPBAR1 in human NCI-H716 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled bile acid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled bile acid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50399965(CHEMBL2181246)
Affinity DataEC50:  10nMAssay Description:Agonist activity at TGR5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)