Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 7Z6C
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591141(CHEMBL5192490 | US20240034730, Compound 29)
Affinity DataIC50: 7.20nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic

US Patent
LigandPNGBDBM50591141(CHEMBL5192490 | US20240034730, Compound 29)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human N-terminal GST-fusion tagged DHODH (31 to 395 residues) expressed in Escherichia coli BL21-GOLD (DE3) using dihydroorotate as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)