Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 7ZIH
TargetTryptophan 5-hydroxylase 1(Human)
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)

Curated by ChEMBL
LigandPNGBDBM357739(AG-01-128/(I-202) | US10214530, Example 18)
Affinity DataIC50: 430nMAssay Description:Inhibition of N-terminal MBP-tagged full length human TPH1 assessed as reduction in 5-HTP formation incubated for 5 to 10 mins by fluorescence microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTryptophan 5-hydroxylase 1(Human)
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)

Curated by ChEMBL
LigandPNGBDBM357739(AG-01-128/(I-202) | US10214530, Example 18)
Affinity DataIC50: 430nMAssay Description:These compounds according to the afore-mentioned examples were tested for tryptophan hydroxylase (TPH) inhibitory activity in a fluorescence-based in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)