Report error Found 6 Enz. Inhib. hit(s) for PDB: 8AV9
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Inhibition of human Biotin-DMRPEIWIAQELRRIGDEFNAYYARR peptide binding to 6XHis-tagged human MCl-1 (171 to 327 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
3D Structure (crystal)TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and biotinylated Bim BH3 peptide interaction usi...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataKi: 0.0760nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of recombinant C-terminal His6x-tagged human Mcl-1 (171 to 327 residues) interaction with biotinylated human Bim (51 to 76 residues) incub...More data for this Ligand-Target Pair
TargetBcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Human)
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 0.5nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Tsinghua University
Curated by ChEMBL
Tsinghua University
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Binding affinity to Mcl-1 (unknown origin)More data for this Ligand-Target Pair