Report error Found 2 Enz. Inhib. hit(s) for PDB: 8D6C
TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Repare Therapeutics
Curated by ChEMBL
Repare Therapeutics
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal human recombinant PKMYT1 (76 to 362 residues) expressed in Escherichia coli (DE3) RIL preincubated with compound for 15 mins...More data for this Ligand-Target Pair
3D Structure (crystal)TargetMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Repare Therapeutics
Curated by ChEMBL
Repare Therapeutics
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 ...More data for this Ligand-Target Pair