Report error Found 4 Enz. Inhib. hit(s) for PDB: 8DHG
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Research and Development
Curated by ChEMBL
Janssen Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of His fused human DHODH expressed in Escherichia coli using DHO as substrate by DCIP absorbance based colorimetry assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Janssen Research and Development
Curated by ChEMBL
Janssen Research and Development
Curated by ChEMBL
Affinity DataKd: 3.30nMAssay Description:Binding affinity to His fused human DHODH expressed in Escherichia coli by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Mouse)
Janssen Research and Development
Curated by ChEMBL
Janssen Research and Development
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of mouse DHODHMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Rat)
Janssen Research and Development
Curated by ChEMBL
Janssen Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of rat DHODHMore data for this Ligand-Target Pair