Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 8DZP
TargetKappa-type opioid receptor(Human)
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50374634(CHEMBL258098)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Human)
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50374634(CHEMBL258098)
Affinity DataKi:  0.600nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Human)
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50374634(CHEMBL258098)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cell membrane after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)