Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 8E3W
TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285044(BDBM485888 | 4-[2-(cyclopropylmethoxy)- 5-methylsu...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285044(BDBM485888 | 4-[2-(cyclopropylmethoxy)- 5-methylsu...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)