Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 8FCB
LigandPNGBDBM50525957(CHEMBL4461515)
Affinity DataEC50:  49nMAssay Description:Agonist activity at recombinant human TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium level after 30 mins by Fura-2 AM/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50525957(CHEMBL4461515)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at rat recombinant TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium accumulation by Fluo4-AM based assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50525957(CHEMBL4461515)
Affinity DataIC50: 122nMAssay Description:Antagonist activity at TRPV4 (unknown origin) expressed in Flp-In-CHO cells assessed as inhibition of GSK1016790A induced Ca2+ influx by calcium imag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)