Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 8FYT
Target5-hydroxytryptamine receptor 1A(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  1.09nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  1.10nMAssay Description:Tested in vitro for its ability to bind to 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A human cloned receptors in HEK293 cells using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity of [3H]- -8-OH-DPAT labelled towards Rat Hippocampal 5-hydroxytryptamine 1A receptor using radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  5.10nMAssay Description:Affinity in displacing [3H]8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
Purdue University

Curated by ChEMBL
LigandPNGBDBM21342((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]8-OH-DPAT by lysergic acid amidesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50241702([N-methyl-3H]LSD | CHEMBL463207 | lsd)
Affinity DataKi:  7.30nMAssay Description:Table S2 shows raw Ki data for the current study combined with data collected from the literature for the ten additional compounds.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2025
Entry Details
PubMedPDB3D3D Structure (crystal)