Report error Found 84 Enz. Inhib. hit(s) for PDB: 8GUR
Displayed 1 to 50 (of 84 total ) | Next | Last >>
Affinity DataKi: 0.150nMAssay Description:Binding affinity to human CB2 cannabinoid receptor using [3H]CP-55940 in HEK293 EBNA transfected cellsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.200nMAssay Description:Agonist activity at recombinant human full length CB2 receptor expressed in HEK293 cell membranes after 2 hrs by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB2 receptor expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.350nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.430nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.439nMAssay Description:Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.540nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cell membrane assessed as increase in GTPgammaS binding pretreated for 30 mins...More data for this Ligand-Target Pair
Affinity DataEC50: 0.576nMAssay Description:Agonist activity at human CB2 receptor expressed in HEK cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKd: 0.590nMAssay Description:Binding affinity to human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
Affinity DataKi: 0.620nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Binding affinity to cannabinoid CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]CP-55,940 from recombinant human full length CB2 receptor expressed in HEK293 cell membranes after 90 mins by topcount methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.690nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Displacement of [3H]CP-55940 form human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Binding assay with hCB1 and hCB2 receptors.More data for this Ligand-Target Pair
Affinity DataEC50: 0.860nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.860nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.880nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:Displacement of [3H]CP55940 from human cannabinoid CB2 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.924nMAssay Description:Binding affinity was determined in vitro against cannabinoid receptor by ability to displace [3H]CP-55940More data for this Ligand-Target Pair
Affinity DataKi: 0.980nMAssay Description:Binding affinity towards cloned human cannabinoid receptor 2More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation using [3H]-cAMP after ...More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at 3xHA tagged human CB2 receptor expressed in CHO-K1 cells assessed as reduction in forskolin-stimulated cAMP accumulation incubate...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in human HEK293T cells co-expressing beta-arrestin2 assessed as beta-arrestin2 recruitmen...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-SR141716A from human CB1 receptor expressed in CHO membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human CB2 receptor expressed in HEK293 cells assessed as decrease in forskolin-stimulated cAMP level stimulated for 30 mins follo...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]CP55,940 from recombinant human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.42nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHO cells after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB2 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHOK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-CP55940 from N-terminal 3HA-tagged human CB2 receptor expressed in human HEK293-EBNA cells incubated for 60 mins by radioligand ...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-CP55940 from N-terminal 3HA-tagged human CB2 receptor expressed in human HEK293-EBNA cells incubated for 60 mins by radioligand ...More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at recombinant human Cb2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP levelsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO cells after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.20nMAssay Description:Agonist activity at CB2 receptor in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.60nMAssay Description:Agonist activity at N-terminal HA-tagged human CB2 receptor expressed in HEK293 cells transfected with YFP-Epac-RLuc assessed as decrease in forskoli...More data for this Ligand-Target Pair
Affinity DataEC50: 6.10nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 6.10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 6.30nMAssay Description:Agonist activity at human recombinant cannabinoid CB2 receptor expressed in HEK cells transfected with CNG assessed as decrease in cAMP level measure...More data for this Ligand-Target Pair