Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 8GW8
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Rat)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM64562(US9428505, Compound 7)
Affinity DataEC50:  2.40E+3nMpH: 7.4Assay Description:Instead of HKRK-B7 cells, LLC-PK46_RATO_PTH1R cells overexpressing rat PTH1R, which were established at Chugai Pharmaceutical, were used to take meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM64562(US9428505, Compound 7)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at recombinant human PTHR1 expressed in pig LLC-PK1 cells assessed as increase in cAMP production measured after 20 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)