Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 8HB0
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50346265((2R,3R,4S,5S,6R)-2-(3-(4-cyclopropylbenzyl)-4-fluo...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50346265((2R,3R,4S,5S,6R)-2-(3-(4-cyclopropylbenzyl)-4-fluo...)
Affinity DataEC50:  1.90nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)