Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 8HLR
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM209857(US9273052, 19 | US9566277, 19)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM209857(US9273052, 19 | US9566277, 19)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM209857(US9273052, 19 | US9566277, 19)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM209857(US9273052, 19 | US9566277, 19)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM209857(US9273052, 19 | US9566277, 19)
Affinity DataIC50: 10.2nMT: 2°CAssay Description:The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM209857(US9273052, 19 | US9566277, 19)
Affinity DataIC50: 10.2nMT: 2°CAssay Description:he assay described below is to determine the activity of the compounds of the present invention for inhibiting the enzyme activity of PARP by using t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)