Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 8IHH
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50220842(3-butyl-1H-pyrazole-5-carboxylic acid | 5-butyl-1H...)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50220842(3-butyl-1H-pyrazole-5-carboxylic acid | 5-butyl-1H...)
Affinity DataEC50:  85nMAssay Description:Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50220842(3-butyl-1H-pyrazole-5-carboxylic acid | 5-butyl-1H...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHydroxycarboxylic acid receptor 3(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50220842(3-butyl-1H-pyrazole-5-carboxylic acid | 5-butyl-1H...)
Affinity DataEC50:  1.17E+4nMAssay Description:Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)