Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 8IXS
TargetKelch-like ECH-associated protein 1(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50614981(CHEMBL5284493)
Affinity DataIC50: 89nMAssay Description:Inhibition of Nrf2-Keap1 Kelch domain (unknown origin) protein-protein interaction in presence of biotin labeled 16mer ETGE peptide AFFAQLQLDEETGEFLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetKelch-like ECH-associated protein 1(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50614981(CHEMBL5284493)
Affinity DataKd:  130nMAssay Description:Binding affinity to biotinylated Keap1 Kelch domain (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)