Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 8JD6
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  9.84E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssayPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  295nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssayPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.09E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssayPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium flux prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human mGlu4 receptor assessed as increase in calcium flux by Fluo-4 AM dye based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  290nMAssay Description:Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.10E+3nMAssay Description:Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  330nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)