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Found
1
Enz. Inhib. hit(s) for PDB:
8PYJ
Target
Insulin-like growth factor 1 receptor
(Human)
Sanofi-Aventis
Curated by
ChEMBL
Ligand
BDBM50340520
(5,5-dimethyl-1-(quinolin-4-ylmethyl)-3-(4-(trifluo...)
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Affinity Data
IC50: 460nM
Assay Description:
Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells by time resolved-fluorescent assay
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Target Info
PDB
KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
PC cid
PC sid
PDB
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In Depth
Date in BDB:
1/6/2013
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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