Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 8W8K
TargetHeat shock protein HSP 90-alpha(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50439621(STA-9090 | GANETESPIB)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant HSP90alpha preincubated for 30 mins followed by FITC-GM addition and mesured after 3 hrs by fluorescence polarization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Fujian Medical University (Fmu)

Curated by ChEMBL
LigandPNGBDBM50439621(STA-9090 | GANETESPIB)
Affinity DataKd:  24nMAssay Description:Binding affinity to HSP90 (unknown origin) by fluorescence quenching methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50439621(STA-9090 | GANETESPIB)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant HSP90alpha (unknown origin) incubated for 24 hrs in presence of 1-FITC3 probe by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Fujian Medical University (Fmu)

Curated by ChEMBL
LigandPNGBDBM50439621(STA-9090 | GANETESPIB)
Affinity DataIC50: 63nMAssay Description:Inhibition of Hsp90 in human MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Fujian Medical University (Fmu)

Curated by ChEMBL
LigandPNGBDBM50439621(STA-9090 | GANETESPIB)
Affinity DataIC50: 63nMAssay Description:Inhibition of Hsp90 in human MG63 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Fujian Medical University (Fmu)

Curated by ChEMBL
LigandPNGBDBM50439621(STA-9090 | GANETESPIB)
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of human HSP90More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)