Report error Found 11 Enz. Inhib. hit(s) for PDB: 8Y6H
Affinity DataIC50: 4.90nMAssay Description:Inhibition of paclitaxel stimulated- P-gp ATPase activity (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 40nMAssay Description:TP_TRANSPORTER: transepithelial transport of digoxin (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 193nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
Affinity DataIC50: 193nMAssay Description:Inhibition of ABCB1 in human KBV1 cells after 10 mins by Calcein-AM microplate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 193nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) in MDR1-expressing MDCK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Inhibition of human P-glycoprotein mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ABCB1-mediated [3H]vinblastine transportation in human Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Inhibition of Pgp measured as inhibition of [3H]vinblastine basolateral to apical transport in Caco-2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Inhibition of human Pgp mediated [3H]vinblastine transport in human Caco-2 cellsMore data for this Ligand-Target Pair